Since evil spirits are invisible, wouldn’t it be great to have an invisible around-the-clock guard who can warn you of a spiritual attack and protect you? Ephesians 6:18 states, “Praying at all times in the Spirit, with all prayer and supplication. To that end, keep alert with all perseverance, making supplication [requests] for all the saints.” Prayer is a forgotten part of God’s armor, but it is essential for using the rest of the armor because that is where spiritual warfare is fought.

When you pray, you become connected to the Spirit of God, called the Holy Spirit, who lives in your soul/heart. The Holy Spirit can see the evil spirits attack and warn you and then help you be victorious when you have the armor of God on. Prayer is how we draw strength from God and rely on Him to protect us. Praying is the key that “activates” the armor. When you don’t rely on God through prayer, you will lose every spiritual battle. I have written many posts on prayer, which you can find in Posts about Prayer.

Unanswered prayer is a spiritual battle we all face. Because evil spirits know that prayer is powerful and connects us to God’s power and the Holy Spirit’s guidance. Therefore, they will put doubts, distractions, and deceptions into your mind to keep you from praying. So, we need to be alert. 1Peter 5:8 states, “Be sober-minded; be watchful. Your adversary, the devil, prowls around like a roaring lion, seeking someone to devour.” He mainly attacks our minds through deception and temptations, which I covered in the last nine spiritual warfare posts.

I. How do you pray constantly? 

Ephesians 6:18 states, “Praying at all times in the Spirit, with all prayer and supplication. To that end, keep alert with all perseverance, making supplication [requests] for all the saints.” I believe praying at all times means always being mindful to turn every thought into prayer. For example, if you see an ambulance, pray for the paramedics and the injured or sick in the ambulance. If someone cuts you off on the highway, pray a blessing of safe travel for them. As you look at the people you walk by, intercede for them. In 1 Thessalonians 5:17, the Apostle Paul encourages us to “pray without ceasing.” And Romans 12:12 states we are to “Rejoice in hope, be patient in tribulation, be constant in prayer.  So if I think about someone, I will pray for them at that moment. I immediately turn my concerns over to God instead of thinking about them and being tempted to be anxious. When I am having trouble with something, I seek God for help and guidance. If I am tempted to be angry, I ask God to take the anger from my heart and give me peace. When I walk by my refrigerator and see the missionary pictures, I will pray for them as I go about my kitchen tasks. And so on.

II. What do you think it means to “pray at all times in the Spirit”? 

There are several ideas about what it means to pray in the Spirit. One scholar said, that “praying in the spirit means to be directed by the spirit to pray for certain things and for certain people.1” Albert Barnes said in his commentary that “praying in the Spirit is to pray with His aid.”  Romans 8:26 states, “Likewise, the Spirit helps us in our weakness. For we do not know what to pray for as we ought, but the Spirit Himself intercedes for us with groanings too deep for words.”

Those in the charismatic circle say praying in the spirit means we pray in “tongues” (a spiritual language). The book of Acts explains how people spoke in tongues, a few places are in Acts 2:4, 2:38, 19:6. 1Corinthians 14:1-2 states, “Pursue love, and earnestly desire the spiritual gifts, especially that you may prophesy. For one who speaks in a tongue speaks not to men but to God; for no one understands him, but he utters mysteries in the Spirit.”  1Corinthians 14:14 states, “For if I pray in a tongue, my spirit prays but my mind is unfruitful.”

We receive the Holy Spirit of God the moment we put our faith in Jesus to be our Lord and Savior. Some biblical scholars say you can have another “baptism/filling of the Spirit” as a separate event given as a gift from God when we ask for it (Luke 11:13). Regardless of what terminology you use, there seem to be separate Holy Spirit infilling events, which causes controversies in some churches.

III. What does it mean to be alert in prayer?

We are to stay alert through prayer because prayer is our guard that protects our thinking. After all, that is where we fight the spiritual war (2Cor. 11:3). When we are not praying, our guard is down, and we become vulnerable to Satan’s unseen attacks. Even Jesus often went alone up into the hills or some other desolate place to pray (Luke 5:16). He knew He needed to commune with His Father.

We, too, need the help of God our Father in heaven to fight against Satan and all the demonic forces of darkness. 2Corinthians 10:4-5 states, “For the weapons of our warfare are not of the flesh but have divine power to destroy strongholds. We destroy arguments and every lofty opinion raised against the knowledge of God and take every thought captive to obey Christ.” The weapons of our warfare are God’s armor and His power through the spoken word. My short book on this website explains how to use prayer to destroy wrong thinking, false beliefs, and strongholds. DISCOVER A NEW REALITY.

We can talk to God about anything; besides, He knows everything and is always with us (Ps. 94:11, 139:2-4). God wants us to make requests because He wants to answer our prayers. Isaiah 65:24 states, “Before they call I will answer; while they are yet speaking, I will hear.”

IV. What do you think it means to “keep alert with all perseverance, making supplications [requests] for all the saints?”

First, to “keep alert” means to watch for opportunities. Second, “with all perseverance” means never becoming discouraged or disheartened and not growing weary of making requests for others. Third, “saints” are those who are the children of God. The following Scriptures call believers in Jesus Christ saints: Ephesians 1:1; 1 Corinthians 1:2; Philippians 1:1; and Colossians 1:2. 

Prayer also involves worship and thankfulness for all God has blessed us with, or thankfulness for the various truths and promises found in the Bible. Praying at all times is easy when you abide in Jesus Christ (John 15) by letting your mind dwell on Him and not on things of the earth. Note, we do not have to be perfect for God to answer our prayers. We need to humble ourselves by abiding (remain in and dwell) through prayer in the heavenly place with Christ and in the Word of God.

2 Chronicles 7:14 states, “If My people who are called by My name humble themselves, and pray and seek My face and turn from their wicked ways, then I will hear from heaven and will forgive their sin and heal their land.”


Most people are told to set aside time for prayer every day, which is a good practice. Jesus took time for prayer. But praying all the time is a different discipline. Though both prayer methods require mental discipline. I can’t stress enough that through prayer, you stay connected to God, who is your refuge in times of trouble and will protect you from the evil one (2Thes. 3:3). Psalm 91:9-10 states, “Because you have made the LORD your dwelling place—the Most High, who is my refuge—no evil shall be allowed to befall you, no plague come near your tent [dwelling].” When you pray continually, you are dwelling with your Lord. 


  1. McDonald, William. (1995) Believers Bible Commentary



Psalm 91 Posts


Can You Be Too Heavenly Minded?

All verses are from the English Standard Bible. If you find my posts and website helpful, please share the links with your friends and family, hopeforcompletehealing.com. The information is copyright protected, and no part of the posts or my book may be reproduced without proper citation to Joyce Hanscom and this website. 

Contact me at hopeforcompletehealing@gmail.com, and ask for a PDF of Eight Prayers from the Bible. The prayers are for the Spirit of wisdom, renewal, spiritual strength, knowledge of His will, virtues of God, salvation for non-believers, 23rd Psalm, and victory. Please leave your name, so I know you are a real person making the request.

Author: Joyce Holzman Hanscom

I teach incarcerated women in the county jail about how to discover a new reality for their lives. Discovering a new reality is achieved when you heal emotions from painful memories and transform negative heart issues. When false beliefs are transformed by truth, then you can love from a pure heart and make wise decisions.

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